Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/1451210158
总结
UGT1A1 *28/*28 + *6/*6 + *1/*6 + *1/*28 is associated with increased likelihood of Neutropenia when treated with FOLFIRI or irinotecan in people with biliary tract neoplasms or Pancreatic Neoplasms as compared to UGT1A1 *1/*1.