Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/1451208260
总结
CYP2D6 *1/*3 + *1/*4 + *1/*5 + *1/*6 + *4/*41 + *6/*10 + *10/*10 + *41/*41 (assigned as intermediate metabolizer phenotype) are associated with increased risk of sedation when treated with ketoprofen and tramadol in people with Pain, Postoperative as compared to CYP2D6 *1/*1 + *1/*2 + *1/*9 + *1/*10 + *1/*17 + *1/*41 + *2/*2 (assigned as normal metabolizer phenotype) .