Patients with the rs1799971 AA genotype may have an increased analgesic response to oxycodone as compared to patients with the AG or GG genotypes. However, another study failed to find an association. This drug-variant pair has been assigned a 鈥渘o recommendation鈥?by CPIC, as it was determined to be not clinically actionable. Other genetic and clinical factors may also affect response to oxycodone.