Both variants of rs1801265 are assigned normal function by CPIC. Patients with the AA genotype and cancer who are treated with fluorouracil, a fluoropyrimidine-based chemotherapy, may not have altered risk of drug toxicity as compared to patients with the AG or GG genotype. However, conflicting evidence has been reported. Other genetic and clinical factors may also influence risk of drug toxicity.,临床等位基因

Both variants of rs1801265 are assigned normal function by CPIC. Patients with the AA genotype and cancer who are treated with fluorouracil, a fluoropyrimidine-based chemotherapy, may not have altered risk of drug toxicity as compared to patients with the AG or GG genotype. However, conflicting evidence has been reported. Other genetic and clinical factors may also influence risk of drug toxicity.

临床注释ID

981201981

基因型等位基因

AA

等位基因的功能