The rs267606619 C allele (also known as the 1494C allele) is assigned as a MT-RNR1 normal risk of aminoglycoside-induced hearing loss allele by CPIC. Patients with the C allele may have a decreased, but not absent, risk of experiencing hearing loss when treated with gentamicin as compared to patients with the 1494T allele. However, conflicting evidence has been reported. MT-RNR1 is a mitochondrial gene and is inherited as a haploid (i.e. there is only ever one allele present). Other genetic and clinical factors may also influence risk of hearing loss when treated with gentamicin.