Both variants of rs72549306 are assigned normal function by CPIC. Patients with the CC genotype may have increased DPYD activity as compared to those with the CA or AA genotype. However, data is limited and evidence for no association exists. However, conflicting evidence has been reported. Other genetic and clinical factors may also influence catalytic activity of DPYD.,临床等位基因

Both variants of rs72549306 are assigned normal function by CPIC. Patients with the CC genotype may have increased DPYD activity as compared to those with the CA or AA genotype. However, data is limited and evidence for no association exists. However, conflicting evidence has been reported. Other genetic and clinical factors may also influence catalytic activity of DPYD.

临床注释ID

1447989732

基因型等位基因

CC

等位基因的功能