The SLCO1B1*5 allele (defined as consisting of rs4149056) is assigned as a no function allele by CPIC. Patients carrying SLCO1B1*5 allele in combination with a normal, no, or increased function allele may have increased exposure to pitavastatin as compared to patients with two normal function alleles. Other genetic or clinical factors may also affect a patient's exposure to pitavastatin. This annotation only covers the pharmacokinetic relationship between SLCO1B1 and pitavastatin and does not include evidence about clinical outcomes.