The SLCO1B1*15 allele (defined as consisting of both rs4149056 and rs2306283) is assigned as a no function allele by CPIC. Patients carrying SLCO1B1*15 allele in combination with a normal, no, or increased function allele may have increased lovastatin acid concentrations as compared to patients with two normal function alleles. This annotation only covers the pharmacokinetic relationship between SLCO1B1 and lovastatin and does not include evidence about clinical outcomes. Other genetic and clinical factors may also influence a patient's lovastatin pharmacokinetics.