The SLCO1B1*1 allele is assigned as a normal function allele by CPIC. Patients with the SLCO1B1*1 allele in combination with another normal function allele may have decreased lovastatin acid concentrations as compared to patients with a no function allele in combination with a normal or increased function allele or with two no function alleles. This annotation only covers the pharmacokinetic relationship between SLCO1B1 and lovastatin and does not include evidence about clinical outcomes. Other genetic and clinical factors may also influence a patient's lovastatin pharmacokinetics.