利培酮,PubMed 中的摘要说明，变体和药物之间的可能关系

利培酮

化学ID

PA451257

化学名称(英)

risperidone

书本上化学名称

利培酮

书本上化学名称(英)

risperidone

变体ID

PA166155747

变体名称

rs6706232

变体类型

变体

变体类型(英)

Variant

变体名称文本

rs6706232

基因身份证

PA37181,PA37180,PA37183,PA37182,PA37178,PA37179,PA37174,PA419

基因符号

UGT1A10,UGT1A5,UGT1A4,UGT1A3,UGT1A9,UGT1A8,UGT1A7,UGT1A6

基因文本

文学ID

15103482

PMID

28696411

文献标题

Combined study of genetic and epigenetic biomarker risperidone treatment efficacy in Chinese Han schizophrenia patients.

出版年

2017

杂志

Translational psychiatry

句子

In our study, rs6706232 was first found related with risperidone treatment in mainland Chinese Han population, allele A accounted for a higher proportion in good responders compared with poor responders at 33.3%, 24.6%, 25.2% in the Henan, Shanghai and total cohort, respectively, which means the G>A mutation might have certain impact on risperidone therapy.

源

PGxMine