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华法林
文献标题
Pharmacogenetics of warfarin in a paediatric population: time in therapeutic range, initial and stable dosing and adverse effects.
杂志
The pharmacogenomics journal
句子
Adult patients from a variety of ethnic backgrounds with the variant allele(s) in one of the recognised polymorphisms in the VKORC1 gene (rs9923231, VKORC1-1639 ), and/or a variant allele(s) in polymorphisms in the CYP2C9 gene (rs1057910 and rs1799853, CYP2C9*2 and *3 respectively) require lower doses of warfarin , -.