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伊立替康
文献标题
Association of UGT1A1*28 polymorphisms with irinotecan-induced toxicities in colorectal cancer: a meta-analysis in Caucasians.
杂志
The pharmacogenomics journal
句子
A six-repeat allele is the most commonly identified (wild type) form; a seven-repeat allele (designated UGT1A1*28) is associated with dramatically reduced expression of UGT1A1, resulting in lower SN-38 glucuronidation.