化学ID

PA449719

化学名称(英)

furosemide

书本上化学名称

呋塞米

书本上化学名称(英)

furosemide

变体ID

rs152728

变体名称

rs152728

变体类型

变体

变体类型(英)

Variant

变体名称文本

rs152728

基因身份证

基因符号

基因文本

文学ID

15096925

PMID

26927285

文献标题

A pharmacogenetic investigation of intravenous furosemide in decompensated heart failure: a meta-analysis of three clinical trials.

出版年

2017

杂志

The pharmacogenomics journal

句子

The primary objective of this pharmacogenetic meta-analysis was to test whether genetic variants previously shown to modulate the diuretic effects of loop diuretics ( SLC12A3 rs1529927, the SCNN1B2 haplotype [rs152728, rs152745, rs238547] and SCNN1G rs5723 and rs5729) are associated with net fluid loss (the total fluid output over 72 hours minus the total fluid input over 72 hours in mL) of a diuretic strategy based on intravenous furosemide at 72 hours after randomization in patients with decompensated HF.

源

PGxMine