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拉帕替尼
文献标题
Comprehensive genome-wide evaluation of lapatinib-induced liver injury yields a single genetic signal centered on known risk allele HLA-DRB1*07:01.
杂志
The pharmacogenomics journal
句子
Previous investigations have identified and confirmed the Class II allele HLA-DRB1 * 07:01 to be strongly associated with lapatinib-induced liver injury; however, the moderate positive predictive value limits its clinical utility.