当前位置:药药网 / 数据中心 / PubMed 中的摘要说明,变体和药物之间的可能关系
氯吡格雷
文献标题
Interindividual variability of CYP2C19-catalyzed drug metabolism due to differences in gene diplotypes and cytochrome P450 oxidoreductase content.
杂志
The pharmacogenomics journal
句子
However, we were unable to demonstrate a significant difference in the formation of 2-oxo-clopidogrel from clopidogrel or CAM from 2-oxo-clopidogrel by HLMs from donors with a CYP2C19*17/*17 diplotype compared with the CYP2C19*1B/*1B diplotype.