化学ID

PA449053

化学名称(英)

clopidogrel

书本上化学名称

氯吡格雷

书本上化学名称(英)

clopidogrel

变体ID

PA165816533

变体名称

CYP2C19*17

变体类型

单倍型

变体类型(英)

Haplotype

变体名称文本

*17

基因身份证

PA124

基因符号

CYP2C19

基因文本

文学ID

15085066

PMID

25001880

文献标题

Clinical outcomes associated with proton pump inhibitor use among clopidogrel-treated patients within CYP2C19 genotype groups following acute myocardial infarction.

出版年

2015

杂志

The pharmacogenomics journal

句子

After limiting cardiac rehospitalizations to non-elective admissions only , the rate of cardiac rehospitalization for PPI users remained significantly higher compared with non-users in clopidogrel-treated Caucasians (14.1% vs. 7.7%, p = 0.00004; HR 1.95, 95% CI 1.36-2.78; p = 0.0002) and within the clopidogrel-treated Caucasian CYP2C19 *17 genotype group (18.3% vs. 6.4%, p = 0.00009; HR 2.48 (95% CI 1.39-4.42; p = 0.002).

源

PGxMine