化学ID

PA451906

化学名称(英)

warfarin

书本上化学名称

华法林

书本上化学名称(英)

warfarin

变体ID

变体名称

NQO1*2

变体类型

单倍型

变体类型(英)

Haplotype

变体名称文本

*2

基因身份证

PA31744

基因符号

NQO1

基因文本

文学ID

PMID

30410385

文献标题

Creating and validating a warfarin pharmacogenetic dosing algorithm for Colombian patients

出版年

2018

杂志

Pharmacogenomics and Personalized Medicine

句子

Other studies in Mexican American, Caribbean Latino, and Brazilian populations have developed algorithms that explain 68%, 70%, 63% of the inter-individual variability in warfarin dosing with the inclusion of CYP4F2*3 , F2 , CYP2C9*5 , CYP2C9*6 , CYP2C9*8 , CYP2C9*1 , and NQO1*2 genotypes plus VKORC1 haplotype and several concurrent medications. , Taken together, those variables add about 11% to the proposed models.

源

PGxMine