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华法林
基因身份证
PA134899581,PA165450635,PA133787052
文献标题
VKORC1 variants as significant predictors of warfarin dose in Emiratis
杂志
Pharmacogenomics and Personalized Medicine
句子
Warfarin inhibits this reductase, limiting the conversion of vitamin K epoxide into vitamin K and consequently decreasing the formation of clotting factors. , Single nucleotide polymorphisms (SNPs) occurring on VKORC1 mainly including rs9923231, rs17708472, rs9934438, and rs2359612 were found to affect the availability or activity of the reductase impacting the anticoagulant effect of drugs targeting this enzyme, like warfarin.