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伊立替康
基因身份证
PA37181,PA37180,PA37183,PA37182,PA420,PA37178,PA37179,PA37174,PA419
基因符号
UGT1A10,UGT1A1,UGT1A5,UGT1A4,UGT1A3,UGT1A9,UGT1A8,UGT1A7,UGT1A6
文献标题
Association of insertion-deletions polymorphisms with colorectal cancer risk and clinical features
杂志
World Journal of Gastroenterology
句子
In particular, INDEL variants in UGT1A1 (rs8175347) were associated with significantly decreased glucuronidation activity, which results in reduced SN-38 clearance and an increased risk of these toxicities in patients homozygous for the Ins allele.