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靶点信息21(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Cytochrome P450 reductase (P450)
TARGTYPE
Discontinued target
SYNONYMS
P450R; NADPH--cytochrome P450 reductase; CYPOR; CPR
FUNCTION
This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.
PDBSTRUC
5FA6; 5EMN; 3QFT; 3QFS; 3QFR
BIOCLASS
NADH/NADPH oxidoreductase
SEQUENCE
MGDSHVDTSSTVSEAVAEEVSLFSMTDMILFSLIVGLLTYWFLFRKKKEEVPEFTKIQTLTSSVRESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDNALVVFCMATYGEGDPTDNAQDFYDWLQETDVDLSGVKFAVFGLGNKTYEHFNAMGKYVDKRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEHFGVEATGEESSIRQYELVVHTDIDAAKVYMGEMGRLKSYENQKPPFDAKNPFLAAVTTNRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQLGKILGADLDVVMSLNNLDEESNKKHPFPCPTSYRTALTYYLDITNPPRTNVLYELAQYASEPSEQELLRKMASSSGEGKELYLSWVVEARRHILAILQDCPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVVVEYETKAGRINKGVATNWLRAKEPAGENGGRALVPMFVRKSQFRLPFKATTPVIMVGPGTGVAPFIGFIQERAWLRQQGKEVGETLLYYGCRRSDEDYLYREELAQFHRDGALTQLNVAFSREQSHKVYVQHLLKQDREHLWKLIEGGAHIYVCGDARNMARDVQNTFYDIVAELGAMEHAQAVDYIKKLMTKGRYSLDVWS
WIKIPATH
WP43:Oxidation by Cytochrome P450
BIOCPATH
PWY-6061:Bile acid biosynthesis, neutral pathway
BIOCPATH
PWY-6076:Vitamin D3 biosynthesis
BIOCPATH
PWY-6398:Melatonin degradation I
BIOCPATH
PWY-6402:Superpathway of melatonin degradation
目标的蛋白质ID
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目标的序列数据
标题 | 内容 |
Cytochrome P450 reductase (P450) |
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