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靶点信息16(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
G-protein coupled receptor 39 (GPR39)
TARGTYPE
Literature-reported target
SYNONYMS
Gprotein coupled receptor 39; GPR39
FUNCTION
Zn(2+) acts as a agonist. Thisreceptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death.
SEQUENCE
MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLCCRLSLQHANHEKRLRVHAHSTTDSARFVQRPLLFASRRQSSARRTEKIFLSTFQSEAEPQSKSQSLSLESLEPNSGAKPANSAAENGFQEHEV
DRUGINFO
GPCR39 pepducins
WIKIPATH
WP1825:GPCR ligand binding
WIKIPATH
WP455:GPCRs, Class A Rhodopsin-like
REACPATH
R-HSA-373076:Class A/1 (Rhodopsin-like receptors)
目标的蛋白质ID
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目标的序列数据
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| G-protein coupled receptor 39 (GPR39) |
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