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靶点信息34(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Urate anion exchanger 1 (URAT1)
TARGTYPE
Successful target
SYNONYMS
UNQ6453/PRO34004; Solute carrier family 22 member 12; Renal-specific transporter; RST; Organic anion transporter 4-like protein; OATL4
FUNCTION
Regulates blood urate levels. Mediates saturable urate uptake by facilitating the exchange of urate against organic anions. Required for efficient urate re-absorption in the kidney.
BIOCLASS
Major facilitator
SEQUENCE
MAFSELLDLVGGLGRFQVLQTMALMVSIMWLCTQSMLENFSAAVPSHRCWAPLLDNSTAQASILGSLSPEALLAISIPPGPNQRPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYDRSIFTSTIVAKWNLVCDSHALKPMAQSIYLAGILVGAAACGPASDRFGRRLVLTWSYLQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAGVMMNTGTLLMEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAESARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLRMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSHLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSLPLPDTIQDVQNQAVKKATHGTLGNSVLKSTQF
DRUGINFO
2-ethyl-3-(4-hydroxy) benzoyl benzofuran derivative 1
DRUGINFO
3-benzyloxyphenyloxoacetic acid derivative 1
DRUGINFO
Benzene sulfonamide derivative 16
DRUGINFO
Benzofurans derivative 1
DRUGINFO
Benzoic acid derivative 1
DRUGINFO
Cycloalkyl acid derivative 1
目标的蛋白质ID
标题 | 内容 |
TARGETID |
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UNIPROID |
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TARGNAME |
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TARGTYPE |
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目标的序列数据
标题 | 内容 |
Urate anion exchanger 1 (URAT1) |
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