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靶点信息29(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Interleukin 7 receptor alpha (IL7R)
TARGTYPE
Clinical trial target
SYNONYMS
Interleukin-7 receptor subunit alpha; IL-7RA; IL-7R-alpha; IL-7R subunit alpha; IL-7R alpha chain; IL-7 receptor subunit alpha; CDw127; CD127 antigen; CD127
FUNCTION
Acts as a receptor for thymic stromal lymphopoietin (TSLP). Receptor for interleukin-7.
PDBSTRUC
5J11; 3UP1; 3DI3; 3DI2
BIOCLASS
Cytokine receptor
SEQUENCE
MTILGTTFGMVFSLLQVVSGESGYAQNGDLEDAELDDYSFSCYSQLEVNGSQHSLTCAFEDPDVNITNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEINNSSGEMDPILLTISILSFFSVALLVILACVLWKKRIKPIVWPSLPDHKKTLEHLCKKPRKNLNVSFNPESFLDCQIHRVDDIQARDEVEGFLQDTFPQQLEESEKQRLGGDVQSPNCPSEDVVITPESFGRDSSLTCLAGNVSACDAPILSSSRSLDCRESGKNGPHVYQDLLLSLGTTNSTLPPPFSLQSGILTLNPVAQGQPILTSLGSNQEEAYVTMSSFYQNQ
KEGGPATH
hsa04060:Cytokine-cytokine receptor interaction
KEGGPATH
hsa04068:FoxO signaling pathway
KEGGPATH
hsa04151:PI3K-Akt signaling pathway
KEGGPATH
hsa04630:Jak-STAT signaling pathway
KEGGPATH
hsa04640:Hematopoietic cell lineage
KEGGPATH
hsa05340:Primary immunodeficiency
WIKIPATH
WP205:IL-7 Signaling Pathway
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04060 |
|
| hsa04068 |
|
| hsa04151 |
|
| hsa04630 |
|
| hsa04640 |
|
| hsa05340 |
|
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP2864 |
|
| WP2673 |
|
| WP2203 |
|
| WP205 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Interleukin 7 receptor alpha (IL7R) |
|