靶点信息16(本栏目收费,不能显示细节,电话13136136841)
靶点信息
标题
内容
相关药物
状态
TARGETID
T84560
FORMERID
TTDR00083
UNIPROID
UCP2_HUMAN
TARGNAME
Mitochondrial uncoupling protein 2 (UCP2)
GENENAME
UCP2
TARGTYPE
Clinical trial target
SYNONYMS
UCPH; UCP 2; Solute carrier family 25 member 8; SLC25A8
FUNCTION
UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.
BIOCLASS
Mitochondrial carrier
SEQUENCE
MVGFKATDVPPTATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHASIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVNAYKTIAREEGFRGLWKGTSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKRALMAACTSREAPF
DRUGINFO
CL-316,243
DRUGINFO
NC-2100
WIKIPATH
WP111:Electron Transport Chain
WIKIPATH
WP1902:Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
NET_PATH
NetPath_14:IL2 Signaling Pathway
INTEPATH
hnf3bpathway:FOXA2 and FOXA3 transcription factor networks
目标的 KEGG 通路数据
标题内容
目标的 Wiki 路径数据
标题内容
WP1902
WP111
目标的蛋白质ID
标题内容
TARGETID
UNIPROID
TARGNAME
TARGTYPE
目标的序列数据
标题内容
Mitochondrial uncoupling protein 2 (UCP2)
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