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靶点信息10(本栏目收费,不能显示细节,电话13136136841)
靶点信息
UNIPROID
IBP1_HUMAN; IBP2_HUMAN; IBP3_HUMAN
TARGNAME
Bone resorption factor (BRF)
GENENAME
IGFBP1; IGFBP2; IGFBP3
TARGTYPE
Discontinued target
SYNONYMS
Insulin-like growth factor-binding protein; IGFBP; IGF-binding protein; IBP
FUNCTION
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.
SEQUENCE
MSEVPVARVWLVLLLLTVQVGVTAGAPWQCAPCSAEKLALCPPVSASCSEVTRSAGCGCCPMCALPLGAACGVATARCARGLSCRALPGEQQPLHALTRGQGACVQESDASAPHAAEAGSPESPESTEITEEELLDNFHLMAPSEEDHSILWDAISTYDGSKALHVTNIKKWKEPCRIELYRVVESLAKAQETSGEEISKFYLPNCNKNGFYHSRQCETSMDGEAGLCWCVYPWNGKRIPGSPEIRGDPNCQIYFNVQN
目标的蛋白质ID
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目标的序列数据
| 标题 | 内容 |
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| Bone resorption factor (BRF) |
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