当前位置：药药网 / 数据中心 /靶点信息(本栏目收费,不能显示细节,电话13136136841)
靶点信息31(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Epiregulin (EREG)
TARGTYPE
Clinical trial target
SYNONYMS
l=Epiregulin; Proepiregulin; EPR
FUNCTION
Stimulates EGFR and ERBB4 tyrosine phosphorylation. Contributes to inflammation, wound healing, tissue repair, and oocyte maturation by regulating angiogenesis and vascular remodeling and by stimulating cell proliferation. Ligand of the EGF receptor/EGFR and ERBB4.
PDBSTRUC
5WB7; 5E8D; 1K37; 1K36
SEQUENCE
MTAGRRMEMLCAGRVPALLLCLGFHLLQAVLSTTVIPSCIPGESSDNCTALVQTEDNPRVAQVSITKCSSDMNGYCLHGQCIYLVDMSQNYCRCEVGYTGVRCEHFFLTVHQPLSKEYVALTVILIILFLITVVGSTYYFCRWYRNRKSKEPKKEYERVTSGDPELPQV
KEGGPATH
hsa04012:ErbB signaling pathway
WIKIPATH
WP2653:PIP3 activates AKT signaling
WIKIPATH
WP2780:Signaling by ERBB2
WIKIPATH
WP2781:Signaling by ERBB4
WIKIPATH
WP673:ErbB Signaling Pathway
REACPATH
R-HSA-1250196:SHC1 events in ERBB2 signaling
REACPATH
R-HSA-1250342:PI3K events in ERBB4 signaling
REACPATH
R-HSA-1250347:SHC1 events in ERBB4 signaling
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP673 |
|
| WP2781 |
|
| WP2780 |
|
| WP2653 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|