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靶点信息72(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Purine nucleoside phosphorylase (PNP)
TARGTYPE
Clinical trial target
SYNONYMS
PNP; Inosine phosphorylase
FUNCTION
The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
PDBSTRUC
5UGF; 5ETJ; 4GKA; 4ECE; 4EB8
BIOCLASS
Pentosyltransferase
SEQUENCE
MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPLPDKAS
DRUGINFO
2'3'-Dideoxyinosine
DRUGINFO
(+/-)-5'-deoxy-4'-fluoro-5'-methylthio-DADMe-ImmH
DRUGINFO
2-Hydroxymethyl-Pyrrolidine-3,4-Diol
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa00230 |
|
| hsa00240 |
|
| hsa00760 |
|
| hsa01100 |
|
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP2006 |
|
| WP2004 |
|
| WP2003 |
|
| WP2002 |
|
| WP1851 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Purine nucleoside phosphorylase (PNP) |
|