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靶点信息31(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Phosphogluconate dehydrogenase (PGD)
TARGTYPE
Successful target
SYNONYMS
PGDH; 6PGDH; 6-phosphogluconate dehydrogenase, decarboxylating; 6-phosphogluconate dehydrogenase
FUNCTION
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
PDBSTRUC
5UQ9; 4GWK; 4GWG; 2JKV
BIOCLASS
CH-OH donor oxidoreductase
SEQUENCE
MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSSYNA
DRUGINFO
(2R)-2-Methyl-4,5-dideoxy
DRUGINFO
4-phospho-D-erythronate
DRUGINFO
5-deoxy-5-phosphono-D-arabinonate
DRUGINFO
6-Phosphogluconic Acid
DRUGINFO
Pyrophosphate 2-
KEGGPATH
hsa00030:Pentose phosphate pathway
KEGGPATH
hsa00480:Glutathione metabolism
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa00030 |
|
| hsa00480 |
|
| hsa01100 |
|
| hsa01130 |
|
| hsa01200 |
|
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP2884 |
|
| WP2882 |
|
| WP1848 |
|
| WP134 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Phosphogluconate dehydrogenase (PGD) |
|