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靶点信息74(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Leukocyte surface antigen Leu-16 (CD20)
TARGTYPE
Successful target
SYNONYMS
Membrane-spanning 4-domains subfamily A member 1; Leu-16; Bp35; B-lymphocyte surface antigen B1; B-lymphocyte antigen CD20
FUNCTION
Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes.
PDBSTRUC
3PP4; 3BKY; 2OSL; 1S8B
BIOCLASS
CD20 calcium channel
SEQUENCE
MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMRESKTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKRTCSRPKSNIVLLSAEEKKEQTIEIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETETNFPEPPQDQESSPIENDSSP
DRUGINFO
Tisagenlecleucel
DRUGINFO
Bevacizumab + Rituximab
目标的蛋白质ID
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目标的序列数据
| 标题 | 内容 |
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| Leukocyte surface antigen Leu-16 (CD20) |
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