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靶点信息101(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Melanocortin receptor 4 (MC4R)
TARGTYPE
Successful target
FUNCTION
Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP). Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH.
PDBSTRUC
2IQW; 2IQV; 2IQU; 2IQS; 2IQR
SEQUENCE
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
DRUGINFO
Methylnaltrexone bromide
目标的 Wiki 路径数据
标题 | 内容 |
WP455 |
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WP24 |
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WP1825 |
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WP1824 |
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目标的蛋白质ID
标题 | 内容 |
TARGETID |
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UNIPROID |
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TARGNAME |
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TARGTYPE |
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目标的序列数据
标题 | 内容 |
Melanocortin receptor 4 (MC4R) |
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