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靶点信息20(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
MHC class I NK cell receptor 2DL1 (CD158A)
TARGTYPE
Clinical trial target
SYNONYMS
p58.1 MHC class-I-specific NK receptor; p58 natural killer cell receptor clones CL-42/47.11; p58 NK receptor CL-42/47.11; Natural killer-associated transcript 1; NKAT1; NKAT-1; Killer cell immunoglobulin-like receptor 2DL1; CD158A; CD158 antigen-like family member A
FUNCTION
Receptor on natural killer (NK) cells for some HLA-C alleles such as w4 and w6. Inhibits the activity of NK cells thus preventing cell lysis.
SEQUENCE
MSLLVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIGEHHDGVSKANFSISRMTQDLAGTYRCYGSVTHSPYQVSAPSDPLDIVIIGLYEKPSLSAQPGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGPKVNGTFQADFPLGPATHGGTYRCFGSFHDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAESRSKVVSCP
KEGGPATH
hsa04612:Antigen processing and presentation
KEGGPATH
hsa04650:Natural killer cell mediated cytotoxicity
KEGGPATH
hsa05332:Graft-versus-host disease
WIKIPATH
WP1829:Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
REACPATH
R-HSA-198933:Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
NET_PATH
NetPath_14:IL2 Signaling Pathway
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04612 |
|
| hsa04650 |
|
| hsa05332 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
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目标的序列数据
| 标题 | 内容 |
|---|
| MHC class I NK cell receptor 2DL1 (CD158A) |
|