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靶点信息48(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Synaptosomal-associated protein 25 (SNAP25)
TARGTYPE
Successful target
SYNONYMS
Synaptosomal-associated 25 kDa protein; Super protein; SUP; SNAP-25; SNAP
FUNCTION
May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells. t-SNARE involved in the molecular regulation of neurotransmitter release.
PDBSTRUC
5W7J; 5W7I; 3ZUR; 3RL0; 3RK3
BIOCLASS
Synaptosomal vesicle fusion pore
SEQUENCE
MAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKEAEKNLTDLGKFCGLCVCPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG
DRUGINFO
Botulinum Toxin Type A
KEGGPATH
hsa04721:Synaptic vesicle cycle
KEGGPATH
hsa04911:Insulin secretion
WIKIPATH
WP1831:Integration of energy metabolism
WIKIPATH
WP1871:Neurotransmitter Release Cycle
WIKIPATH
WP2267:Synaptic Vesicle Pathway
WIKIPATH
WP2665:Botulinum neurotoxicity
WIKIPATH
WP2685:GABA synthesis, release, reuptake and degradation
WIKIPATH
WP481:Insulin Signaling
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP706 |
|
| WP481 |
|
| WP2685 |
|
| WP2665 |
|
| WP2267 |
|
| WP1871 |
|
| WP1831 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Synaptosomal-associated protein 25 (SNAP25) |
|