当前位置：药药网 / 数据中心 /靶点信息(本栏目收费,不能显示细节,电话13136136841)
靶点信息28(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Placenta growth factor (PlGF)
TARGTYPE
Successful target
SYNONYMS
SHGC-10760; PlGF-2; PLGF; PGFL; D12S1900
FUNCTION
It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration.
SEQUENCE
MPVMRLFPCFLQLLAGLALPAVPPQQWALSAGNGSSEVEVVPFQEVWGRSYCRALERLVDVVSEYPSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTMQLLKIRSGDRPSYVELTFSQHVRCECRHSPGRQSPDMPGDFRADAPSFLPPRRSLPMLFRMEWGCALTGSQSAVWPSSPVPEEIPRMHPGRNGKKQQRKPLREKMKPERCGDAVPRR
DRUGINFO
2-Methyl-2,4-Pentanediol
KEGGPATH
hsa04014:Ras signaling pathway
KEGGPATH
hsa04015:Rap1 signaling pathway
KEGGPATH
hsa04151:PI3K-Akt signaling pathway
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04014 |
|
| hsa04015 |
|
| hsa04151 |
|
| hsa04510 |
|
| hsa05200 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Placenta growth factor (PlGF) |
|