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靶点信息21(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Lymphocyte IgE receptor (CD23)
TARGTYPE
Clinical trial target
SYNONYMS
Low affinity immunoglobulin epsilon Fc receptor soluble form; Low affinity immunoglobulin epsilon Fc receptor; Immunoglobulin Ebinding factor; FcepsilonRII; FCER2; Ctype lectin domain family 4 member J; CD23; BLAST2
FUNCTION
Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
PDBSTRUC
5LGK; 4KI1; 4J6Q; 4J6P; 4J6N
SEQUENCE
MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERAARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRLKSQDLELSWNLNGLQADLSSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHVDYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESMGPDSRPDPDGRLPTPSAPLHS
KEGGPATH
hsa04640:Hematopoietic cell lineage
KEGGPATH
hsa05169:Epstein-Barr virus infection
WIKIPATH
WP2718:Signaling by NOTCH2
WIKIPATH
WP2806:Human Complement System
REACPATH
R-HSA-2197563:NOTCH2 intracellular domain regulates transcription
NET_PATH
NetPath_15:IL3 Signaling Pathway
NET_PATH
NetPath_16:IL4 Signaling Pathway
NET_PATH
NetPath_19:IL-7 Signaling Pathway
目标的蛋白质ID
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目标的序列数据
| 标题 | 内容 |
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| Lymphocyte IgE receptor (CD23) |
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