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靶点信息20(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Claudin-18 (CLDN18)
TARGTYPE
Clinical trial target
SYNONYMS
UNQ778/PRO1572; Claudin18
FUNCTION
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
SEQUENCE
MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVRQSSGFTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGFKASTGFGSNTKNKKIYDGGARTEDEVQSYPSKHDYV
DRUGINFO
CAR-CLD18 T cell
KEGGPATH
hsa04514:Cell adhesion molecules (CAMs)
KEGGPATH
hsa04530:Tight junction
KEGGPATH
hsa04670:Leukocyte transendothelial migration
KEGGPATH
hsa05160:Hepatitis C
REACPATH
R-HSA-420029:Tight junction interactions
NET_PATH
NetPath_16:IL4 Signaling Pathway
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04514 |
|
| hsa04530 |
|
| hsa04670 |
|
| hsa05160 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
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| UNIPROID |
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| TARGNAME |
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| TARGTYPE |
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