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靶点信息74(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Ecto-5'-nucleotidase (CD73)
TARGTYPE
Clinical trial target
SYNONYMS
NT5; CD73 antigen; 5'-nucleotidase; 5'-NT
FUNCTION
Exhibits AMP-, NAD-, and NMN-nucleosidase activities. Hydrolyzes extracellular nucleotides into membrane permeable nucleosides.
PDBSTRUC
4H2I; 4H2G; 4H2F; 4H2B; 4H1Y
BIOCLASS
Phosphoric monoester hydrolase
SEQUENCE
MCPRAARAPATLLLALGAVLWPAAGAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANIKAKGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLNSSIPEDPSIKADINKWRIKLDNYSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMINNNLRHTDEMFWNHVSMCILNGGGIRSPIDERNNGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYGQSTGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTKCRVPSYDPLKMDEVYKVILPNFLANGGDGFQMIKDELLRHDSGDQDINVVSTYISKMKVIYPAVEGRIKFSTGSHCHGSFSLIFLSLWAVIFVLYQ
DRUGINFO
PMID28870136-Compound-36
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa00230 |
|
| hsa00240 |
|
| hsa00760 |
|
| hsa01100 |
|
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP2848 |
|
| WP2005 |
|
| WP2004 |
|
| WP2002 |
|
| WP1851 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Ecto-5'-nucleotidase (CD73) |
|