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靶点信息28(本栏目收费,不能显示细节,电话15274084725)
靶点信息
TARGNAME
Vascular endothelial growth factor D (VEGFD)
TARGTYPE
Clinical trial target
SYNONYMS
c-Fos-induced growth factor; VEGFD; VEGF-D; FIGF
FUNCTION
Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formationof the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.
SEQUENCE
MYREWVVVNVFMMLYVQLVQGSSNEHGPVKRSSQSTLERSEQQIRAASSLEELLRITHSEDWKLWRCRLRLKSFTSMDSRSASHRSTRFAATFYDIETLKVIDEEWQRTQCSPRETCVEVASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNTSTSYISKQLFEISVPLTSVPELVPVKVANHTGCKCLPTAPRHPYSIIRRSIQIPEEDRCSHSKKLCPIDMLWDSNKCKCVLQEENPLAGTEDHSHLQEPALCGPHMMFDEDRCECVCKTPCPKDLIQHPKNCSCFECKESLETCCQKHKLFHPDTCSCEDRCPFHTRPCASGKTACAKHCRFPKEKRAAQGPHSRKNP
KEGGPATH
hsa04014:Ras signaling pathway
KEGGPATH
hsa04015:Rap1 signaling pathway
KEGGPATH
hsa04060:Cytokine-cytokine receptor interaction
KEGGPATH
hsa04151:PI3K-Akt signaling pathway
KEGGPATH
hsa04510:Focal adhesion
KEGGPATH
hsa05200:Pathways in cancer
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04014 |
|
| hsa04015 |
|
| hsa04060 |
|
| hsa04151 |
|
| hsa04510 |
|
| hsa05200 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Vascular endothelial growth factor D (VEGFD) |
|