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靶点信息13(本栏目收费,不能显示细节,电话13136136841)

靶点信息

标题

内容

相关药物

状态

TARGETID

T55936

FORMERID

TTDR00622

UNIPROID

PSS_MYCTU

TARGNAME

Mycobacterium CDP-diacylglycerol-inositol phosphatidyltransferase (MycB pssA)

GENENAME

MycB pssA

TARGTYPE

Clinical trial target

SYNONYMS

pssA; PtdIns synthase; Phosphatidylinositol synthase; PI synthase

FUNCTION

Catalyzes the biosynthesis of phosphatidylinositol (ptdins) as well as ptdins:inositol exchange reaction. May thus act to reduce an excessive cellular ptdins content. The exchange activity is due to the reverse reaction of ptdins synthase.

BIOCLASS

Kinase

ECNUMBER

EC 2.7.8.8

SEQUENCE

MIGKPRGRRGVNLQILPSAMTVLSICAGLTAIKFALEHQPKAAMALIAAAAILDGLDGRVARILDAQSRMGAEIDSLADAVNFGVTPALVLYVSMLSKWPVGWVVVLLYAVCVVLRLARYNALQDDGTQPAYAHEFFVGMPAPAGAVSMIGLLALKMQFGEGWWTSGWFLSFWVTGTSILLVSGIPMKKMHAVSVPPNYAAALLAVLAICAAAAVLAPYLLIWVIIIAYMCHIPFAVRSQRWLAQHPEVWDDKPKQRRAVRRASRRAHPYRPSMARLGLRKPGRRL

DRUGINFO

Myo-inositol

DRUGINFO

Zn2+

目标的 KEGG 通路数据

标题	内容

目标的 Wiki 路径数据

标题	内容

目标的蛋白质ID

标题	内容
TARGETID	T55936
UNIPROID	PSS_MYCTU
TARGNAME	Mycobacterium CDP-diacylglycerol-inositol phosphatidyltransferase (MycB pssA)
TARGTYPE	Clinical Trial target

目标的序列数据

标题	内容
Mycobacterium CDP-diacylglycerol-inositol phosphatidyltransferase (MycB pssA)	MIGKPRGRRGVNLQILPSAMTVLSICAGLTAIKFALEHQPKAAMALIAAAAILDGLDGRVARILDAQSRMGAEIDSLADAVNFGVTPALVLYVSMLSKWPVGWVVVLLYAVCVVLRLARYNALQDDGTQPAYAHEFFVGMPAPAGAVSMIGLLALKMQFGEGWWTSGWFLSFWVTGTSILLVSGIPMKKMHAVSVPPNYAAALLAVLAICAAAAVLAPYLLIWVIIIAYMCHIPFAVRSQRWLAQHPEVWDDKPKQRRAVRRASRRAHPYRPSMARLGLRKPGRRL

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