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靶点信息14(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
B-type natriuretic peptide (BNP)
TARGTYPE
Literature-reported target
SYNONYMS
Natriuretic peptides B; NPPB; Gammabrain natriuretic peptide; BNP32; BNP(529); BNP(132)
FUNCTION
Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
BIOCLASS
Natriuretic peptide family
SEQUENCE
MDPQTAPSRALLLLLFLHLAFLGGRSHPLGSPGSASDLETSGLQEQRNHLQGKLSELQVEQTSLEPLQESPRPTGVWKSREVATEGIRGHRKMVLYTLRAPRSPKMVQGSGCFGRKMDRISSSSGLGCKVLRRH
KEGGPATH
hsa04022:cGMP-PKG signaling pathway
WIKIPATH
WP1544:MicroRNAs in cardiomyocyte hypertrophy
目标的蛋白质ID
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目标的序列数据
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| B-type natriuretic peptide (BNP) |
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