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靶点信息20(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
MHC class I NK cell receptor 2DL2 (CD158b1)
TARGTYPE
Clinical trial target
SYNONYMS
p58 natural killer cell receptor clone CL-43; p58 NK receptor CL-43; Natural killer-associated transcript 6; NKAT6; NKAT-6; Killer cell immunoglobulin-like receptor 2DL2; CD158B1; CD158 antigen-like family member B1
FUNCTION
Receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus preventing cell lysis.
PDBSTRUC
2DLI; 2DL2; 1EFX
SEQUENCE
MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVIGNPSNSWPSPTEPSSKTGNPRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYAELPNAESRSKVVSCP
KEGGPATH
hsa04612:Antigen processing and presentation
KEGGPATH
hsa04650:Natural killer cell mediated cytotoxicity
KEGGPATH
hsa05332:Graft-versus-host disease
WIKIPATH
WP1829:Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
REACPATH
R-HSA-198933:Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
NET_PATH
NetPath_14:IL2 Signaling Pathway
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04612 |
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| hsa04650 |
|
| hsa05332 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
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| UNIPROID |
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| TARGNAME |
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| TARGTYPE |
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目标的序列数据
| 标题 | 内容 |
|---|
| MHC class I NK cell receptor 2DL2 (CD158b1) |
|