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靶点信息58(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Quinone reductase 1 (NQO1)
TARGTYPE
Clinical trial target
SYNONYMS
Qui reductase 1; QR1; Phylloquinone reductase; Phylloqui reductase; NMOR1; NAD(P)H:quinone oxidoreductase 1; NAD(P)H dehydrogenase [quinone] 1; Menadione reductase; DTD; DT-diaphorase 1; DT-diaphorase; DIA4; Azoreductase
FUNCTION
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
PDBSTRUC
6FY4; 5FUQ; 5EAI; 5EA2; 5A4K
BIOCLASS
NADH/NADPH oxidoreductase
SEQUENCE
MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKLKDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERVFIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFCGFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMKKEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK
DRUGINFO
Coenzyme Q10 analog
DRUGINFO
2-Benzyl-1-hydroxy-3H-benzo[f]chromen-3-one
DRUGINFO
3-(3,4-Dimethylbenzyl)-4-hydroxy-2H-chromen-2-one
DRUGINFO
3-Benzyl-4-hydroxy-2H-benzo[h]chromen-2-one
DRUGINFO
3-Benzyl-4-hydroxy-2H-chromen-2-one
DRUGINFO
3-Benzyl-4-hydroxy-6,7-dimethyl-2H-chromen-2-one
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP697 |
|
| WP408 |
|
| WP3 |
|
| WP2884 |
|
| WP2882 |
|
| WP2873 |
|
| WP2864 |
|
| WP2693 |
|
| WP2586 |
|
| WP2436 |
|
| WP2100 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Quinone reductase 1 (NQO1) |
|