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靶点信息

标题

内容

相关药物

状态

TARGETID

T51146

FORMERID

TTDI01872

UNIPROID

FUT4_HUMAN

TARGNAME

Fucosyltransferase IV (CD15)

GENENAME

FUT4

TARGTYPE

Successful target

SYNONYMS

Galactoside 3-L-fucosyltransferase; Fucosyltransferase 4; FucT-IV; Fuc-TIV; FCT3A; ELFT; ELAM-1 ligand fucosyltransferase; Alpha-(1,3)-fucosyltransferase 4

FUNCTION

May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.

BIOCLASS

Glycosyltransferases

ECNUMBER

EC 2.4.1.-

SEQUENCE

MRRLWGAARKPSGAGWEKEWAEAPQEAPGAWSGRLGPGRSGRKGRAVPGWASWPAHLALAARPARHLGGAGQGPRPLHSGTAPFHSRASGERQRRLEPQLQHESRCRSSTPADAWRAEAALPVRAMGAPWGSPTAAAGGRRGWRRGRGLPWTVCVLAAAGLTCTALITYACWGQLPPLPWASPTPSRPVGVLLWWEPFGGRDSAPRPPPDCRLRFNISGCRLLTDRASYGEAQAVLFHHRDLVKGPPDWPPPWGIQAHTAEEVDLRVLDYEEAAAAAEALATSSPRPPGQRWVWMNFESPSHSPGLRSLASNLFNWTLSYRADSDVFVPYGYLYPRSHPGDPPSGLAPPLSRKQGLVAWVVSHWDERQARVRYYHQLSQHVTVDVFGRGGPGQPVPEIGLLHTVARYKFYLAFENSQHLDYITEKLWRNALLAGAVPVVLGPDRANYERFVPRGAFIHVDDFPSASSLASYLLFLDRNPAVYRRYFHWRRSYAVHITSFWDEPWCRVCQAVQRAGDRPKSIRNLASWFER

DRUGINFO

D07WLI

99mTc-fanolesomab

Approved

目标的 KEGG 通路数据

标题	内容

目标的 Wiki 路径数据

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目标的蛋白质ID

标题	内容
TARGETID	T51146
UNIPROID	FUT4_HUMAN
TARGNAME	Fucosyltransferase IV (CD15)
TARGTYPE	Successful target

目标的序列数据

标题	内容
Fucosyltransferase IV (CD15)	MRRLWGAARKPSGAGWEKEWAEAPQEAPGAWSGRLGPGRSGRKGRAVPGWASWPAHLALAARPARHLGGAGQGPRPLHSGTAPFHSRASGERQRRLEPQLQHESRCRSSTPADAWRAEAALPVRAMGAPWGSPTAAAGGRRGWRRGRGLPWTVCVLAAAGLTCTALITYACWGQLPPLPWASPTPSRPVGVLLWWEPFGGRDSAPRPPPDCRLRFNISGCRLLTDRASYGEAQAVLFHHRDLVKGPPDWPPPWGIQAHTAEEVDLRVLDYEEAAAAAEALATSSPRPPGQRWVWMNFESPSHSPGLRSLASNLFNWTLSYRADSDVFVPYGYLYPRSHPGDPPSGLAPPLSRKQGLVAWVVSHWDERQARVRYYHQLSQHVTVDVFGRGGPGQPVPEIGLLHTVARYKFYLAFENSQHLDYITEKLWRNALLAGAVPVVLGPDRANYERFVPRGAFIHVDDFPSASSLASYLLFLDRNPAVYRRYFHWRRSYAVHITSFWDEPWCRVCQAVQRAGDRPKSIRNLASWFER

标题

内容

Fucosyltransferase IV (CD15)

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