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靶点信息27(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Thyroid peroxidase (TPO)
TARGTYPE
Successful target
SYNONYMS
Thyroperoxidase; TPO
FUNCTION
Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4).
SEQUENCE
MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQRNLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQAVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL
DRUGINFO
Propylthiouracil
DRUGINFO
TPO gene plasmid
KEGGPATH
hsa00350:Tyrosine metabolism
KEGGPATH
hsa01100:Metabolic pathways
KEGGPATH
hsa04918:Thyroid hormone synthesis
KEGGPATH
hsa05320:Autoimmune thyroid disease
WIKIPATH
WP1981:Thyroxine (Thyroid Hormone) Production
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa00350 |
|
| hsa01100 |
|
| hsa04918 |
|
| hsa05320 |
|
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP2849 |
|
| WP2848 |
|
| WP2693 |
|
| WP1981 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Thyroid peroxidase (TPO) |
|