靶点信息20(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Connective tissue growth factor (CTGF)
TARGTYPE
Clinical trial target
SYNONYMS
Long; Insulin-like growth factor-binding protein 8; IGFBP8; IGFBP-8; IGF-binding protein 8; IBP-8; Hypertrophic chondrocyte-specific protein 24; HCS24; CCN2; CCN family member 2
FUNCTION
Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Major connective tissue mitoattractant secreted by vascular endothelial cells.
SEQUENCE
MTAASMGPVRVAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCDPHKGLFCHFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTVVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESLYYRKMYGDMA
KEGGPATH
hsa04390:Hippo signaling pathway
WIKIPATH
WP2738:YAP1- and WWTR1 (TAZ)-stimulated gene expression
WIKIPATH
WP2797:Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
WIKIPATH
WP2804:Hair Follicle Development: Induction (Part 1 of 3)
WIKIPATH
WP2840:Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
REACPATH
R-HSA-1989781:PPARA activates gene expression
REACPATH
R-HSA-2032785:YAP1- and WWTR1 (TAZ)-stimulated gene expression
NET_PATH
NetPath_7:TGF_beta_Receptor Signaling Pathway
INTEPATH
amb2_neutrophils_pathway:amb2 Integrin signaling
INTEPATH
tgfbrpathway:TGF-beta receptor signaling
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP2840 |
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| WP2804 |
|
| WP2797 |
|
| WP2738 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
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目标的序列数据
| 标题 | 内容 |
|---|
| Connective tissue growth factor (CTGF) |
|