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靶点信息28(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Strychnine-binding glycine receptor (GLRA1)
TARGTYPE
Successful target
SYNONYMS
Strychnine-insensitive glycine receptor; Strychnine binding subunit; Glycine receptor 48 kDa subunit; GLRA1
FUNCTION
The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).
PDBSTRUC
4X5T; 2M6I; 2M6B; 1VRY; 1MOT
BIOCLASS
Neurotransmitter receptor
SEQUENCE
MYSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNQ
DRUGINFO
THIOCOLCHICOSIDE
DRUGINFO
10-methoxy-ginkgolide C
DRUGINFO
3,14-DIDEHYDROGINKGOLIDE A
DRUGINFO
3-demethoxy-3D-glucopyranosylaminothiocolchicine
DRUGINFO
3-demethoxy-3-D-lyxopyranosylaminothiocolchicine
DRUGINFO
3-demethoxy-3-D-mannopyranosylaminothiocolchicine
目标的蛋白质ID
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目标的序列数据
| 标题 | 内容 |
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| Strychnine-binding glycine receptor (GLRA1) |
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