靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

TARGETID

T49072

FORMERID

TTDR00562

UNIPROID

UR2R_HUMAN

TARGNAME

Urotensin II receptor (UTS2R)

GENENAME

UTS2R

TARGTYPE

Clinical trial target

SYNONYMS

Urotensin-II receptor GPR14; UTS2R; UR-II-R; G protein coupled receptor 14

FUNCTION

High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.

BIOCLASS

GPCR rhodopsin

SEQUENCE

MALTPESPSSFPGLAATGSSVPEPPGGPNATLNSSWASPTEPSSLEDLVATGTIGTLLSAMGVVGVVGNAYTLVVTCRSLRAVASMYVYVVNLALADLLYLLSIPFIVATYVTKEWHFGDVGCRVLFGLDFLTMHASIFTLTVMSSERYAAVLRPLDTVQRPKGYRKLLALGTWLLALLLTLPVMLAMRLVRRGPKSLCLPAWGPRAHRAYLTLLFATSIAGPGLLIGLLYARLARAYRRSQRASFKRARRPGARALRLVLGIVLLFWACFLPFWLWQLLAQYHQAPLAPRTARIVNYLTTCLTYGNSCANPFLYTLLTRNYRDHLRGRVRGPGSGGGRGPVPSLQPRARFQRCSGRSLSSCSPQPTDSLVLAPAAPARPAPEGPRAPA

DRUGINFO

GSK1440115

DRUGINFO

SB-436811

DRUGINFO

PALOSURAN

Discontinued in Phase 2

DRUGINFO

D04LSH

SAR101099

Discontinued in Phase 1

DRUGINFO

Ac-[CFWKFC]-NH2

DRUGINFO

Ac-[CFWkYC]-NH2

DRUGINFO

AC-7954

DRUGINFO

Ac-FWKY-NH2

DRUGINFO

Ac-SFWKYS-NH2

DRUGINFO

Ac-WKY-NH2

目标的 KEGG 通路数据

标题	内容
hsa04080	Neuroactive ligand-receptor interaction

目标的 Wiki 路径数据

标题	内容
WP2664	Gastrin-CREB signalling pathway via PKC and MAPK
WP1825	GPCR ligand binding
WP1824	GPCR downstream signaling
WP117	GPCRs, Other

目标的蛋白质ID

标题	内容
TARGETID	T49072
UNIPROID	UR2R_HUMAN
TARGNAME	Urotensin II receptor (UTS2R)
TARGTYPE	Clinical Trial target

目标的序列数据

标题	内容
Urotensin II receptor (UTS2R)	MALTPESPSSFPGLAATGSSVPEPPGGPNATLNSSWASPTEPSSLEDLVATGTIGTLLSAMGVVGVVGNAYTLVVTCRSLRAVASMYVYVVNLALADLLYLLSIPFIVATYVTKEWHFGDVGCRVLFGLDFLTMHASIFTLTVMSSERYAAVLRPLDTVQRPKGYRKLLALGTWLLALLLTLPVMLAMRLVRRGPKSLCLPAWGPRAHRAYLTLLFATSIAGPGLLIGLLYARLARAYRRSQRASFKRARRPGARALRLVLGIVLLFWACFLPFWLWQLLAQYHQAPLAPRTARIVNYLTTCLTYGNSCANPFLYTLLTRNYRDHLRGRVRGPGSGGGRGPVPSLQPRARFQRCSGRSLSSCSPQPTDSLVLAPAAPARPAPEGPRAPA

最新招商产品更多>>