靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

TARGETID

T39610

FORMERID

TTDS00432

UNIPROID

CALM1_HUMAN; CALM2_HUMAN; CALM3_HUMAN

TARGNAME

Calmodulin (CALM)

GENENAME

CALM

TARGTYPE

Successful target

SYNONYMS

CaM; CALM2

FUNCTION

Calmodulin mediates the control of a largenumber of enzymes by ca(2+). Among the enzymes to be stimulated by the calmodulin-ca(2+) complex are a number of protein kinases and phosphatases.

BIOCLASS

Calmodulin-dependent secretion

SEQUENCE

MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK

DRUGINFO

Aprindine

DRUGINFO

Halofantrine

DRUGINFO

Trifluoperazine

DRUGINFO

2-Methyl-2,4-Pentanediol

DRUGINFO

2-Methyl-2-Propanol

DRUGINFO

Acetate Ion

DRUGINFO

Cacodylate Ion

DRUGINFO

Calmidazolium

DRUGINFO

MYRISTIC ACID

DRUGINFO

N-Trimethyllysine

目标的 KEGG 通路数据

标题	内容
hsa04014	Ras signaling pathway
hsa04015	Rap1 signaling pathway
hsa04020	Calcium signaling pathway
hsa04022	cGMP-PKG signaling pathway
hsa04024	cAMP signaling pathway
hsa04070	Phosphatidylinositol signaling system
hsa04114	Oocyte meiosis
hsa04261	Adrenergic signaling in cardiomyocytes
hsa04270	Vascular smooth muscle contraction
hsa04713	Circadian entrainment
hsa04720	Long-term potentiation
hsa04722	Neurotrophin signaling pathway
hsa04728	Dopaminergic synapse
hsa04740	Olfactory transduction
hsa04744	Phototransduction
hsa04750	Inflammatory mediator regulation of TRP channels
hsa04910	Insulin signaling pathway
hsa04912	GnRH signaling pathway
hsa04915	Estrogen signaling pathway
hsa04916	Melanogenesis
hsa04921	Oxytocin signaling pathway
hsa04922	Glucagon signaling pathway
hsa04970	Salivary secretion
hsa04971	Gastric acid secretion
hsa05010	Alzheimer's disease
hsa05031	Amphetamine addiction
hsa05034	Alcoholism
hsa05133	Pertussis
hsa05152	Tuberculosis
hsa05214	Glioma

目标的 Wiki 路径数据

标题	内容
WP2777	Translocation of GLUT4 to the Plasma Membrane
WP2776	Visual phototransduction
WP2759	Fc epsilon receptor (FCERI) signaling
WP2754	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
WP2746	Signaling by the B Cell Receptor (BCR)
WP2741	Inositol phosphate metabolism
WP2688	DAG and IP3 signaling
WP1978	Opioid Signalling
WP1864	Muscle contraction
WP1850	Metabolism of nitric oxide
WP1848	Metabolism of carbohydrates

目标的蛋白质ID

标题	内容
TARGETID	T39610
UNIPROID	CALM1_HUMAN; CALM2_HUMAN; CALM3_HUMAN
TARGNAME	Calmodulin (CALM)
TARGTYPE	Successful target

目标的序列数据

标题	内容
Calmodulin (CALM)	MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK

最新招商产品更多>>