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靶点信息47(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Ribonucleoside-diphosphate reductase M2 (RRM2)
TARGTYPE
Successful target
SYNONYMS
Ribonucleotide reductase small subunit; Ribonucleotide reductase small chain; Ribonucleoside-diphosphate reductase subunit M2; RR2
FUNCTION
Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling. Provides the precursors necessary for DNA synthesis.
PDBSTRUC
3VPO; 3VPN; 3VPM; 3OLJ; 2UW2
BIOCLASS
CH/CH(2) oxidoreductase
SEQUENCE
MLSLRVPLAPITDPQQLQLSPLKGLSLVDKENTPPALSGTRVLASKTARRIFQEPTEPKTKAAAPGVEDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGKTNFFEKRVGEYQRMGVMSSPTENSFTLDADF
DRUGINFO
Gallium maltolate
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa00230 |
|
| hsa00240 |
|
| hsa00480 |
|
| hsa01100 |
|
| hsa04115 |
|
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP404 |
|
| WP2446 |
|
| WP1851 |
|
| WP1601 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Ribonucleoside-diphosphate reductase M2 (RRM2) |
|