TARGETID

T32247

FORMERID

TTDS00485

UNIPROID

CALCR_HUMAN

TARGNAME

Calcitonin receptor (CALCR)

GENENAME

CALCR

TARGTYPE

Successful target

SYNONYMS

CT-R

FUNCTION

The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin. This is a receptor for calcitonin.

PDBSTRUC

6NIY; 5UZ7; 5II0

BIOCLASS

GPCR secretin

SEQUENCE

MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVGRKKMMDAQYKCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRRPSNRSARAAAAAAEAGDIPIYICHQEPRNEPANNQGEESAEIIPLNIIEQESSA

DRUGINFO

Calcitonin Human

DRUGINFO

Salmon Calcitonin

DRUGINFO

DACRA 089

DRUGINFO

TJN-220

DRUGINFO

CGNLSTCBLGTYTQDF[DKFHO]YPQTAIGVGAP-amide

DRUGINFO

CGNLSTCBLGTYTQDFNKFHZYPQTAIGVGAP-amide

DRUGINFO

CGNLSTCMLGTYTQDFc[DKFHK]FPQTAIGVGAP-amide

DRUGINFO

CGNLSTCMLGTYTQDFc[DKFHO]FPQTAIGVGAP-amide

DRUGINFO

CGNLSTCMLGTYTQDFNKFHTFPQTAIGVGAP-amide