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靶点信息26(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Interleukin-15 (IL15)
TARGTYPE
Clinical trial target
FUNCTION
Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA. In neutrophils, stimulates phagocytosis probably by signaling through the IL15 receptor, composed of the subunits IL15RA, IL2RB and IL2RG, which results in kinase SYK activation. Cytokine that stimulates the proliferation of T-lymphocytes.
PDBSTRUC
4GS7; 2Z3R; 2Z3Q; 2XQB
BIOCLASS
Cytokine: interleukin
SEQUENCE
MRISKPHLRSISIQCYLCLLLNSHFLTEAGIHVFILGCFSAGLPKTEANWVNVISDLKKIEDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHDTVENLIILANNSLSSNGNVTESGCKECEELEEKNIKEFLQSFVHIVQMFINTS
KEGGPATH
hsa04060:Cytokine-cytokine receptor interaction
KEGGPATH
hsa04630:Jak-STAT signaling pathway
KEGGPATH
hsa04668:TNF signaling pathway
KEGGPATH
hsa04672:Intestinal immune network for IgA production
KEGGPATH
hsa05166:HTLV-I infection
KEGGPATH
hsa05168:Herpes simplex infection
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04060 |
|
| hsa04630 |
|
| hsa04668 |
|
| hsa04672 |
|
| hsa05166 |
|
| hsa05168 |
|
| hsa05323 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Interleukin-15 (IL15) |
|